A St John Ambulance spokeswoman said a person was taken to Rotorua Hospital in a serious condition. Two ambulances were called to the scene at 11.49am.
A guest of the motel said he was going to his car when a man came running towards him from the street, clutching his heart.
"He said, 'help, I've been stabbed' but I didn't believe him at first because he had a hoodie on.