They were treated at the scene, but St John was called back two hours later to reassess the first two patients, and two more who had fallen to the suspected carbon monoxide poisoning.
All four were taken to Christchurch Hospital for further assessment, the spokesman said.
An investigation into what started the blaze in the meal hold of the Nelson-based factory trawler at 5.24am yesterday is ongoing.
It was towed back into port last night after all 43 crew abandoned ship.