Ellen Degeneres is the latest celebrity to defend Prince Harry and Meghan Markle from criticism.

The talk show host took to Instagram to share a post about the royal couple.

"Portia and I met Prince Harry and Meghan in England to talk about their work on wildlife conservation. They were the most down-to-earth, compassionate people," she wrote.

"Imagine being attacked for everything you do, when all you're trying to do is make the world better."

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Degeneres' social media post follows close after Sir Elton John lashed out over the treatment of Prince Harry and Meghan Markle - and compared it to the "intrusion" which led to Princess Diana's "untimely death".

In a series of Twitter posts overnight, Sir Elton revealed he paid for the Duke and Duchess of Sussex to travel by private jet to visit his $26 million home in Nice.

Elton John has spoken out in defence of
Elton John has spoken out in defence of "eco-friendly" Prince Harry and Meghan Markle after they were slammed for taking a private jet to his home in Nice. Photo / Getty Images

The Rocket Man singer, 72, said he provided the luxury 12-seater Cessna plane, that would have cost more than $36,000 to hire, due to the "high level of much-needed protection".

Sir Elton launched the passionate defence of the couple online and begged for "fair coverage" after photos emerged of them boarding a private jet with son Archie.

He said: "After a hectic year continuing their hard work and dedication to charity, David and I wanted the young family to have a private holiday inside the safety and tranquillity of our home.

"To maintain a high level of much-needed protection, we provided them with a private jet flight."

Last month, another celebrity publicly defended the royal couple.

After Markle was accused of diva-like behaviour at Wimbledon, Serena Wiliams was asked by one reporter whether Markle would watch her play in the finals given the "negative media" surround her last appearance.

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Serena Williams and Meghan Markle have been longtime friends. Photo / Supplied
Serena Williams and Meghan Markle have been longtime friends. Photo / Supplied

"You know I didn't know there was negative media out there," Williams replied. "Every time I see her name attached to anything I don't read it."

The tennis superstar also praised the Duchess — who she has been close with since meeting at a celebrity volleyball event in 2014 — for being a good person.

"She couldn't be a better friend to me — low moments, high moments she's always there and that's all I want to be to her," she said.