Mask-to-mask with Spider-Man and Deadpool

Deadpool-Captain America mash-up adds Ryan Reynolds to Civil War. Photo / NZ Herald

At long last, we come mask-to-mask with Spider-Man and Deadpool in a fan-made video that seamlessly mashes them together with Captain America: Civil War.

YouTuber Zach Ace created it and based on an animated GIF by Reddit user riceandnori.

The clip is 45 seconds long and drops Ryan Reynolds' cheeky character in Civil War's airport battle, where he jokes with Tom Holland's Spider-Man.

Deadpool from Fox Studios. Photo / Supplied

"What are you doing here?" a puzzled Spidey asks.

Deadpool merely shrugs and says, "I know, right?"

Some rights issues have kept Deadpool and the Avengers crew in separate boxes.

Fox holds the rights to Deadpool, along with the X-Men and Fantastic Four characters, while Disney-owned Marvel Studios is home to Captain America, Iron Man, Thor, and company.

However, there is an upcoming movie in production called Spider-Man: Homecoming and is a co-production between Marvel and Sony.

In a Twitter Q&A earlier this year, Reynolds and the Deadpool filmmakers said they hope for future crossovers.

"I could definitely imagine doing something with Spider-Man at some point," Reynolds said.

Producer Simon Kinberg has said he inquired about "visitation rights" to Spider-Man, adding, "I would love to see it."

Fans on Youtube commented on the mashup video saying:

"Thought this was gonna be some poorly made clickbait video. Turned out to be well made and hilarious" says Cyborg Lizard.

Eric Heil also says "so freaking good, these two need to team up so badly."