Grimes, whose real name is Claire Boucher, revealed a friend had sadly died during the pandemic, and she was away from friends and family when she passed away.
"It is certainly very demanding to be pregnant in the middle of a pandemic," the musician said. "It's hard not to be able to see friends and family.
"A friend of mine recently died and it was a nightmare not being able to be close to her loved ones. It won't be easy in the hospital, I don't go into details but I feel very empathetic with those who are going through this phase," she said.
"And I trust what the maternity wards are doing to manage the situation, I have great respect for the work of the doctors."
The singer said she hoped there might be some positive outcomes from the global pandemic, including "a reduction in consumerism".
"If people fly less, it can only be good. The same goes for petrol cars and everything else," she said.