"Back in the saddle again. Thank you to all the experts who helped me get here. It's no wonder I don't want to deal with all that being a lady entails sometimes. I'm a mum. I work like crazy. And the first thing to go is usually yourself," she wrote.
"I love this job because it forces me to put back into myself, even if it's really for someone else like Sheila. I feel so grateful to have a job I love. I know how lucky I am and I never take it for granted. Period. Becoming her took weeks and weeks. It gets harder the older you get. But working hard is always worth it. OK. Time to be cool. Because I'm usually not. But she is. So I will be. You know ... fake it til you make it. But don't ever stop short!!!!!!!" she added.
Barrymore, who has been working in Hollywood for more than four decades, has become one of the most refreshing celebrities on Instagram, constantly empowering her 7.4 million followers with truthful messages about what goes into being a celebrity.
Instead of just posting a picture of her perfect manicure yesterday, the actress decided to add an empowering and hilarious message to the picture.
"Gosh, being a girl is time consuming. No wonder I let it all go," she wrote, adding the hashtag "It takes a village".
And when the actor visited the salon to get her regrowth sorted, her daughter Olive came along for the trip, with the hairdresser putting conditioner in her four-year-old's hair for "solidarity".