The fact the athletes do not feature in the picture has got many fired up online, saying it is "ridiculous" they have used able-bodied models rather than the genuine athletes.
However those involved aren't fazed by the outcry, saying it has helped to generate publicity for the event which was the goal all along.
"Participating in the campaign was an honour for me. The atmosphere in the studio was total happiness and pride," said Vogue Brazil's art director Clayton Carneiro.
"For those who do not know, the idea of the campaign came from the paralympic ambassador, Cleo Pires. We knew it would be a punch in the stomach, but we were there for a good cause, after all, almost no one bought tickets to see the Paralympic Games."
Brazilian table tennis player Bruninha Alexandre said she was proud to be part of the campaign and posted a picture of the smiling foursome on Instagram.
Vogue Brazil
It's not the first time Vogue has become the centre of a Photoshop saga. In April a picture of Victoria Beckham made headlines from Vogue China after it appeared something was missing - although others claimed it was just an optical illusion.
The Rio Paralympics start on September 7.