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In one instance of backlash, Minecraft users expressed anger online in June after thinking Mojang was changing the way it let users charge other players. Persson said he was "confused."
Now Persson plans to leave Mojang and return to game- developing competitions and small Web experiments. He said today that if he comes close to something that starts to gain traction, he'll "probably abandon it immediately."
Microsoft's deal to buy Stockholm-based Mojang is projected to close late this year.
"Thank you for turning Minecraft into what it has become, but there are too many of you, and I can't be responsible for something this big," Persson's note said, shortly after Microsoft announced the acquisition. "It's not about the money. It's about my sanity."
A rapid rise to fame isn't always easy. Mobile car-booking startup Uber Technologies Inc.'s Chief Executive Officer Travis Kalanick said on September 8 at a technology conference that the stress of competing against incumbents is his worst enemy.
"Stress will kill me," he said.
Uber was founded in 2009 and has since expanded to more than 140 cities. In June, it raised $1.2 billion in a round of financing that valued the company at $17 billion.
Persson, who handed over the main Minecraft developer duties to colleague Jens Bergensten in 2012 to focus on other projects, is an active Twitter user, posting random photos of a ratty sock and a record turntable.
"I'm not an entrepreneur," Persson said. "I'm not a CEO. I'm a nerdy computer programmer who likes to have opinions on Twitter."
-Bloomberg