The attack contradicts proponents of blockchain, including the Government's science office.
Prof Roubini said the nickname "s---coins", used by cryptocurrency traders referring to less valuable coins, was "a grave insult to manure".
His scathing attack came as the cryptocurrency market took a battering off the back of tumbling global stock markets. Bitcoin dropped as much as 6.9 per cent to $6,080 ($9,345), its lowest point in two months. At its peak late last year Bitcoin was worth US$20,000.
Traders claim Bitcoin's selling point is that its decentralised nature leaves it immune from stock market volatility, acting more like a "digital gold".
But it appears investors are using traditional equity strategies, suggesting the crypto market could dip further if the stock markets continue downward.
Matt Newton, market analyst at cryptocurrency exchange platform eToro, said the fall was "a sign that the markets are working" and that "much of the 'good news' is currently happening behind the scenes".
Governments are mulling whether to regulate cryptocurrencies, which critics claim are vehicles for scams and money laundering.