"This is another example of how broader economic uncertainty is having an impact on economic activity," Eric Fine, managing director of Van Eck G-175 strategies in New York, told Reuters.
The IMF kept its estimate for the US pace of expansion at 2 per cent this year and 2.3 per cent in 2013, as forecast July 3.
Among results released today were those of Citigroup. Shares of the third-largest US bank gained more than 1 per cent after its second-quarter profit surpassed expectations.
In late afternoon trading in New York, the Dow Jones Industrial Average fell 0.24 per cent¸ the Standard & Poor's 500 Index slipped 0.11 per cent, and the Nasdaq Composite Index shed 0.26 per cent.
Among stocks gaining was Human Genome Sciences as GlaxoSmithKline agreed to acquire its long-time partner after a sweetened offer of US$3 billion. Shares of Human Genome rose more than 4 per cent.
In another healthcare deal, private equity firm TPG said it would buy US-based Par Pharmaceutical for US$1.9 billion. Par shares soared more than 36 per cent.
In Europe the Stoxx 600 Index ended the day with a 0.2 per cent gain for the session.
Euro zone inflation data, holding steady at 2.4 per cent in June, underpinned the appeal of German bunds.
Germany's two-year yield fell one basis point to minus 0.055 per cent after earlier declining to a record-low minus 0.06 per cent, according to Bloomberg, while the three-year yield dropped as low as minus 0.022 per cent, and the five-year rate hit a record low 0.27 per cent.
"The general economic backdrop is poor, so people can't get too excited about the periphery," Eric Wand, a fixed-income strategist at Lloyds Banking Group in London, told Bloomberg News. "General risk sentiment is keeping the core underpinned and investors are looking to rotate through the core and semi-core to find yield."