The Ministry for Primary Industries said four officials from China's Certification and Accreditation Administration would arrive next month and visit seven dairy and infant formula-making facilities.
Fonterra and Westland Milk Products are among the firms whose facilities will be audited. One laboratory and a farm will also be visited.
It is a systems audit, meaning only a sample selection of manufacturing operations will be inspected.
The audit comes ahead of a new requirement that all dairy and infant formula manufacturers producing product for China be registered with the Chinese authorities by May 1.
The audit and registration process applies to all countries exporting products to China, not just NZ, and the ministry said it was not a response to Fonterra's botulism false alarm.
NZ Infant Formula Exporters Association chairman Michael Barnett said businesses were facing a lot of uncertainty before the audit.
He blamed big industry players - whom he would not name - for spreading rumours that the Chinese audit process would "knock out the little guys". That was an unlikely result of the audit, Barnett added.
Fonterra's group director for food safety and quality, Ian Palliser, said the Chinese were expected to inspect three of the dairy co-op's sites, including its Hamilton Canpac facility, where infant formula is made.
"It's all part of a reasonably normal process," Palliser said. "What's new about it is this is the Chinese doing it for the first time."