Cristiane Souza described to Brazil's RJ TV how her husband Jose Augusto, 41, lost all feeling shortly after taking the first bite.
"My husband was the first to say he couldn't feel his tongue, then his face, and then his arms. Then his legs went dead and he couldn't stand up any more. It was terrifying.
"My brother-in-law was the same. He didn't even make it out the door. We had to carry them out and rush them to hospital in a car," she said, explaining they had invited the entire family round because the fish looked so "tasty".
Grandmother Maria do Carmo said: "We had no idea it was a pufferfish. They're all in a critical condition. My grandson, my daughter, and my son-in-law, they are all in hospital. We're praying for a miracle.
"We put the fish on the table in the yard outside and everyone dived in. They were all saying how delicious it was. I didn't eat it because I was waiting until everyone had tried it."
Pufferfish, or 'Fugu', is a delicacy in Japan. It is strictly controlled and only chefs who have qualified after three years training can prepare a meal featuring the fish.
Statistics from the Tokyo Bureau of Social Welfare and Public Health indicate 20 to 44 incidents of 'fugu' poisoning every year between 1996 and 2006 in Japan - however a single incident can hide multiple casualties.
There is no known cure for the poison, which paralyses the body while leaving the victim, who gradually suffocates, awake. Victims are hospitalised and their stomachs emptied before being fed activated charcoal to bind the toxin. They are also put on life support until the poison wears off.
- Independent