Police officers were called to the hotel, and the toddler was taken to a hospital where she was pronounced dead.
Officer Michelle Montalvo from Altamonte Springs police said the situation was tragic and urged struggling families to ask for help.
"It's very tragic, it's a 3-year-old, a very young, young child. Sixteen-year-old is also young. A mother loses both daughters in one night because the 16-year-old was arrested that night," Montalvo said.
"If you feel frustrated, reach out to your resources, reach out to your family members, reach out to your village to prevent something as tragic as what happened this weekend."
The teenager appeared in court earlier this week, where a judge ruled that there was probable cause for arrest and ordered for her to be held in a juvenile detention facility until her next appearance on August 8.
- Additional reporting, NZ Herald