Some were critically injured and were being triaged on arrival at Darwin’s airport, she said.
“We acknowledge that this is a terrible incident,” Fyles said.
“The Northern Territory government stands by to offer whatever assistance is required.”
Australian Prime Minister Anthony Albanese said only Americans were injured when the Bell Boeing V-22 Osprey tiltrotor aircraft crashed during Exercise Predators Run, which involves the militaries of the United States, Australia, Indonesia, the Philippines and East Timor.
“The initial reports suggest that the incident involves just US defence force personnel,” Albanese said.
“Our focus as a government and as the department of defence is very much on incident response and on making sure that every support and assistance is given at this difficult time,” he added.
Melville is part of the Tiwi Islands, which along with Darwin are the focus of the exercise that involves 2500 troops.
The Osprey that crashed was one of two that had flown from Darwin to Melville on Sunday, Murphy said.
Around 150 U.S. Marines are currently based in Darwin and up to 2500 rotate through the city every year.
The US military was also taking part in a multination military exercise in July when four Australia personnel were killed in an army MRH-90 Taipan helicopter crash off the northeast Australian coast.