Mackay health authorities have warned of a recent increase in the number of hospital patients complaining of adverse effects associated with the synthetics.
The fatalities prompted police to warn that synthetic drugs, commonly bought over the internet, are covered under drugs misuse legislation.
Detective Acting Inspector Sam Bliss yesterday said the drug was not legal despite its availability over the internet and in suburban shops.
"The chemical compounds found in these drugs are dangerous and are not herbal or natural alternatives to 'real drugs'," he said.
"They contain synthetic compounds which are toxic and extremely dangerous."
Synthetic cannabis products have been banned in New Zealand, with the exception of products that have passed a strict safety testing regime, since last May.