Melania's spokesperson, Stephanie Grisham, took to Twitter to deny the allegations of relationship trouble, calling the reports "fake news".
The laundry list of salacious and flat-out false reporting about Mrs Trump by tabloid publications and TV shows has seeped into "mainstream media" reporting," Grisham said.
"She is focused on her family & role as FLOTUS - not the unrealistic scenarios being peddled daily by the fake news."
The porn star at the centre of the scandal, Stormy Daniels (real name Stephanie Clifford), is scheduled to be interviewed on the popular talk show Jimmy Kmmel Live! after Donald Trump's State of the Union address on Tuesday.