Anouzla is known for his secular outlook, so many see the charges as punishment for his past criticism of King Mohammed VI.
Morocco, a popular tourist destination, is generally considered more stable and open than its North African neighbors, but it still ranks low on media freedom indexes.
However, in the past few years there has been an explosion in online journalism, with Anouzla's Lakome site leading the way.
This year alone Anouzla's site broke the story of the king's accidental pardon of a convicted Spanish child molester, warned about a post-Arab Spring crackdown in the country, and criticized the king's frequent trips to France.
Anouzla appeared before the investigative judge Tuesday, and he will return to court on Wednesday.