Iranian state television reported Amos also met Foreign Minister Mohammad Javad Zarif and stressed the importance of Iran providing assistance to regional countries like Syria. Zarif told Amos about Iran's humanitarian efforts so far in Syria, the report said.
Iran is key regional backer of Syrian President Bashar Assad in the country's civil war. It has occasionally sent humanitarian aid to Syria in the past.
In a statement, Amos said she asked for the Iranian government's help in obtaining "better access for aid operations" in Syria.
"As others continue to pursue a political solution to the conflict in Syria, I can only stress the massive human cost," she said.