He asked Russia's Investigative Committee to probe whether he had suffered intentional poisoning but no criminal case was opened.
Mr Kara-Murza was an ally of the late opposition politician Boris Nemtsov, who was shot dead close to the Kremlin in 2015.
Until last year he was deputy chairman of the Parnas liberal party led by former prime minister turned Kremlin critic Mikhail Kasyanov.
He now works as a co-ordinator for the Open Russia foundation of Mikhail Khodorkovsky, a former oil tycoon who served a decade in jail after openly opposing President Vladimir Putin.
Mr Kara-Murza's father last week told the Moskovsky Komsomolets daily that his son's latest collapse could be a result of the earlier incident.
"It's just that the poisoning two years ago didn't pass without a trace. My son's health is weakened," said Mr Kara-Murza's father, who is also called Vladimir.
Mr Kara-Murza's hospitalisation drew the attention of hawkish US senators who used it to warn new President Donald Trump against getting too cosy with Russian President Vladimir Putin.
In 2016 Chechen strongman and Kremlin loyalist Ramzan Kadyrov prompted outrage by posting a video on Instagram of Mr Kara-Murza and Parnas party leader Kasyanov in the cross hairs of a sniper scope.