Having lost the previous election in 2011, she has spent much of this presidential campaign touring the country drumming up support and rallying its rural poor.
Her opponent, by contrast, is nicknamed "El Gringo" - the American - for his ties to the US. He has tried to counter this by adopting a guinea pig as his election mascot - the animal is a national delicacy for Peruvians - and his supporters wear Inca costumes at rallies.
The son of Polish Jews who fled the Nazis, he is still seen as an outsider. From 1969 the Oxford-educated economist lived in exile in the US, heading investment banks and private firms. Kuczynski's wife, Nancy Lange, is a cousin of the double Oscar-winning actress Jessica Lange while Kuczynski's cousin is French film director Jean-Luc Godard.
Fujimori, married to an American consultant for IBM, became first lady at just 19 when her parents divorced. Her father Alberto Fujimori, 77, ruled Peru with an iron fist from 1990 until 2000. Praised for saving it from Shining Path guerrillas and salvaging the economy, he is currently serving 25 years in prison for death squad killings, having earlier been given six years for abuse of power. He claims the charges were politically motivated.
Kuczynski claims that if the 23 million voters today elect Fujimori as president it will mean "the return of dictatorship".
Fujimori said: "I want to be president of Peru to work for change - to build a great, prosperous country that is united and reconciled."