Illegal migrants who arrive in Italy across the Mediterranean, and who are subsequently unable to rent a house or find a job while they wait for asylum applications to be processed, are regularly "exploited" by the mafia, he said.
Just as "prohibition in America produced Al Capone, [the lack of] permits for migrants is producing a new form of organised crime - traffickers, and then mafia men who run detention centres", he said.
Some 224,000 migrants and refugees have crossed the Mediterranean to Europe so far this year, the United Nations said yesterday. That number is already higher than the total for the whole of 2014, when 219,000 people made the journey.
EU commissioners called on Europe to find the "collective courage" to keep promises made in May after a similar shipwreck claimed the lives of 800 migrants: "Migration is not a popular or pretty topic. It is easy to cry in front of your TV set when witnessing these tragedies.
"It is harder to stand up and take responsibility," they said.
In addition to expanding EU naval operations, the commission will hold a November summit in Malta with key African countries from which migrants travel.
Italy has repeatedly pleaded for more EU resources to manage the growing migrant crisis unfolding on its shores. Separately, the Italian navy yesterday rescued 381 migrants from another fishing vessel in distress 30 nautical miles off Libya.