Roache, who has played Ken Barlow since 1960, emerged from court flanked by his children to say: "In these situations there are no winners and I think we should all be much kinder to ourselves. Now if you will excuse me, I would like to get back to work."
Trying Roache over allegations dating back 50 years was a high-stakes gamble for the CPS which has backfired with potentially far-reaching consequences. John Cooper, QC, a leading barrister, said: "The CPS must consider each particular case on its merits and will not be overly affected by individual verdicts, although they will be well aware of the developing catalogue of acquittals in the most recent historical cases."
Christine Hamilton, wife of former Tory MP Neil Hamilton, who has also faced false sex-abuse allegations, said: "There does feel like there is an element of the witch hunt going on here.
"The authorities let people down over Jimmy Savile and I do wonder if we are now seeing the result of an over-compensation in the way they are pursuing cases."
Ken Morley, who played Reg Holdsworth in Coronation Street, said: "Considering the Michael Le Vell farce, they should be careful about the waste of taxpayers' money.
"My heart goes out to Bill. We all knew it was nonsense from the outset."
Nazir Afzal, the Chief Crown Prosecutor for the North West and the CPS national lead on child sexual exploitation, denied being a "celeb hunter" following the Le Vell case last year.
Yesterday he said: "When serious allegations are made and the evidence in a case passes the prosecution test it is right that a jury considers the evidence.
"We have a duty to those who make complaints of serious offences to listen to the allegations, and assess the evidence against the same evidential standards we use for all criminal cases, no matter who makes the complaint, or who the complaint is against.
"This case was treated like any other - what mattered were the allegations and the evidence and nothing else, and we fully respect the decisions of the jury."
Roache will be able to resume his career on Coronation Street. ITV said: "We look forward to talking to Bill soon about his return to work."