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Home / World

Covid 19: US moves closer to vaccines for kids under 5

AP
15 Jun, 2022 09:57 PM5 mins to read

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Covid-19 vaccines may soon be available for US infants and preschoolers. Photo / AP
Covid-19 vaccines may soon be available for US infants and preschoolers. Photo / AP

Covid-19 vaccines may soon be available for US infants and preschoolers. Photo / AP

Covid-19 shots for US infants, toddlers and preschoolers moved a step closer this week.

The Food and Drug Administration's vaccine advisers gave a thumbs-up to vaccines from Moderna and Pfizer for the littlest kids.

The outside experts voted unanimously that the benefits of the shots outweigh any risks for children under 5 - that's roughly 18 million youngsters. They are the last age group in the US without access to Covid 19 vaccines and many parents have been anxious to protect their little children.

If all the regulatory steps are cleared, shots should be available next week.

"This is a long-awaited vaccine," said one panel member, Dr Jay Portnoy of Children's Hospital in Kansas City, Missouri. "There are so many parents who are absolutely desperate to get this vaccine and I think we owe it to them to give them a choice to have the vaccine if they want to."

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A boy receives a dose of China's Sinovac Covid-19 vaccine at a community vaccination centre in Hong Kong. Photo / AP
A boy receives a dose of China's Sinovac Covid-19 vaccine at a community vaccination centre in Hong Kong. Photo / AP

Dr Peter Marks, FDA's vaccine chief, opened the meeting with data showing a "quite troubling surge" in young children's hospitalisations during the Omicron wave, and noted 442 children under 4 have died during the pandemic. That's far fewer than adult deaths, but should not be dismissed in considering the need for vaccinating the youngest kids, he said.

"Each child that's lost essentially fractures a family," Marks said.

While endorsing the vaccines, some panel members said they believe chances are minimal for severe illness and death in young children.

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"Risks from vaccination are very low, but so are risks from Covid-19 for the youngest kids," said Dr Cody Meissner of Tufts University.

FDA reviewers said both brands appear to be safe and effective for children as young as 6 months old in analyses posted ahead of the all-day meeting. Side effects, including fever and fatigue, were generally minor in both, and less common than seen in adults.

The two vaccines use the same technology but there are differences. In a call with reporters earlier this week, vaccine experts noted that the shots haven't been tested against each other, so there's no way to tell parents if one is superior.

"You can't compare the vaccines directly," said Dr Jesse Goodman of Georgetown University, a former FDA vaccine chief.

If the FDA agrees with its advisers and authorises the shots, there's one more step. The Centers for Disease Control and Prevention will decide on a formal recommendation after its own advisers vote on Saturday. If the CDC signs off, shots could be available as soon as Monday or Tuesday at doctor's offices, hospitals and pharmacies.

Pfizer's vaccine is for children 6 months through 4 years; Moderna's vaccine is for 6 months through 5 years.

Moderna's shots are one-quarter the dose of the company's adult shots. Two doses appeared strong enough to prevent severe illness but only about 40 per cent to 50 per cent effective at preventing milder infections. Moderna added a booster to its tests and expects to eventually offer one.

Pfizer's shots are just one-tenth its adult dose. Pfizer and partner BioNTech found that two shots didn't provide enough protection in testing, so a third was added during the Omicron wave.

Pfizer's submitted data found no safety concerns and suggested that three shots were 80 per cent effective in preventing symptomatic coronavirus infections. But that was based on just 10 Covid-19 cases; the calculation could change as more cases occur in the company's ongoing studies.

Several advisers, noting that protection is low after two Pfizer doses, worried that some parents might end up skipping the third shot, or mistakenly thinking their kids are better protected between shots, leaving them vulnerable.

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Educating parents must be done "very very carefully so that they are not misled about what the vaccines actually provide", said Dr Archana Chatterjee of Rosalind Franklin University.

The same FDA panel backed Moderna's half-sized shots for ages 6 to 11 and full-sized doses for teens. If authorised by the FDA, it would be the second option for those age groups. Currently, Pfizer vaccine is their only choice.

The nation's vaccination campaign started in December 2020 with the rollout of adult vaccines from Pfizer and Moderna, with health care workers and nursing home residents first in line. Teens and school-age children were added last year.

Moderna said in April that it is also seeking regulatory approval outside the US for its little kid shots. According to the World Health Organisation, 12 countries already vaccinate kids under 5, with other brands.

In the US, it remains uncertain how many parents want their youngest vaccinated. By some estimates, three-quarters of all children have already been infected. And only about 29 per cent of children aged 5 to 11 have been vaccinated since Pfizer's shots opened to them last November, a rate far lower than public health authorities consider ideal.

Dr Nimmi Rajagopal, a family medicine physician at Cook County Health in Chicago, said she's been preparing parents for months.

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"We have some that are hesitant, and some that are just raring to go," she said.

- AP

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