A New Zealand-led study published overnight in the journal Nature Communications has now shed further light on this potential.
By studying rocks at different elevations beside the East Antarctic sheet, the research team concluded that a period of rapid glacier thinning occurred in the recent geological past, and persisted for several centuries.
Of particular concern was the potential for "marine ice sheet instability", where an initial retreat of ice margins into deepening valleys could lead to continued, unstable ice loss.
The new research, led by Victoria Postdoctoral Research Fellow Dr Richard Jones, indicated that the processes leading to instability could be initiated by just minor climate warming.
"The finding is very important for predicting Antarctica's future contribution to sea level change," Dr Jones said.
"Particularly when considering that the EAIS contains enough vulnerable ice to raise sea level by tens of metres.
"It might only require a small amount of climate variation to initiate runaway ice loss, and it could continue for centuries to millennia."
While this process had been posited for many years, the study presented the first directly recorded evidence that it has taken place in the past, providing new insight into the future behaviour of rapidly changing parts of Antarctica today.
A major strength of the study was combining numerical modelling experiments that simulate glacier retreat with geological data processed in Victoria University's world-class cosmogenic nuclide laboratory.
The laboratory studies rare isotopes produced through the interaction of cosmic radiation with minerals on the Earth's surface, which allows for the calculation of the age of a rock surface.
"Most research has previously focused on the West Antarctic Ice Sheet, which makes these observations from East Antarctica all the more significant."