In the CBS interview, Assad said his forces were not in the area of the chemical weapons attack Aug. 21, saying "our soldiers in another area were attacked chemically. ... But in the area where they said the government used chemical weapons, we only had video and we only have pictures and allegations. We're not there."
Kerry said Assad's denial is "contradicted by fact."
Asked if chemical warfare could be one repercussion from an American intervention in Syria, Assad told anchorman Charlie Rose: "That depends if the rebels or the terrorists in this region or any other group have it. It could happen. "
"You are going to pay the price if you are not wise with dealing with terrorists," he said.
Assad also said the current incident brings to mind memories of the arguments for intervention that President George W. Bush's administration made over a decade ago in connection with President Saddam Hussein's Iraq.
Assad said Kerry's statements reminded him about "the big lie" that Secretary of State Colin Powell said to the United Nations about Saddam's weapons of mass destruction.
Assad also said the majority of Americans "don't want a war anywhere, not only against Syria."
He said Washington's credibility is "at an all-time low."