"Travel, as we knew it, has changed," said the newspaper.
"In that vein, our 52 Places list will be different in 2021."
With so much uncertainty as to when international travel will re-open, particularly to US travellers, the magazine has decided to look back on travel memories to create the list.
This year they will be compiling "52 love letters to travel", for which they are taking submissions from destinations around the world.
It can be either a famous tourism destination or somewhere that's completely unknown, all they ask for the submission is that it is a place you can pen a love letter to. If you have a photo to share of the destination of desire, even better.
Ideally these love letters will outline both something you miss, and something misunderstood about the location.
There have been many mishaps in previous years which have led to the list shrinking from 52. In 2018 year a deterioration in diplomatic relations between Iran and the US saw its writers being banned from Tehran, after its inclusion on the list.
Last year the newspaper cancelled plans to send writers to visit these locations, saying that it could no longer justify the air travel and carbon footprint. After a year of climate protests, Times Travel editor Amy Virshup said sending a traveller to see these places was unconscionable, calling 2019 "the year the travel world woke up to the implications of climate change."