All guests over 12 and without formal written exemption, will need to show proof of vaccine using the My Vaccine Pass.
Any guests who wish to cancel over these new requirements will be refunded, said the reserve.
"We have a whole gambit of operations, some of which will never need CVC. Going onto the beach is something you can't control," Ross told the Herald.
As a Crown Entity on public land the parks and access to beaches will be open to all, however guests will be required to need to be fully vaccinated to camp on site.
"The Kaiteriteri Store is classed as a supermarket and access cannot be restricted based on vaccination."
On Friday Kaiteriteri in the Tasman Bay will begin at Orange level, meaning that travel for recreation — including overnight camping is permitted.
At level Orange there are no vaccine mandates or caps on guests for accommodation including campsites.
However other businesses including outdoor activities and sports clubs are subjected to limits on visitor numbers, unless they choose to follow My Vaccine Pass requirements, and only allow fully vaccinated people to enter.