The 36-year-old later shared a photo of his closed fist to his Instagram story with "Satisfaction" written above it.
Jodi Silva of the Houston Police Department told MMA Fighting Lewis reported the incident to police at around 9.30am local time after hearing banging noises coming from the driver's side of the car when he returned home from a workout.
"Mr. Lewis says he went over to the suspect, struck him, placed him onto the ground until the police arrived," Silva said. "That's the nicest way to put it."
MMA reporter Ariel Helwani tweeted Lewis told him he "knocked the man out".
The alleged thief was taken to hospital and faces a charge of criminal mischief because, as Silva added, "our winner did not get into the vehicle".
Lewis is on a four-fight winning streak in the UFC, his latest victory coming courtesy of a brutal KO of Curtis Blaydes in February.
Prior to that he secured a TKO win over Alexey Oleynik last August, following on from points victories over Ilir Latifi and Blagoy Ivanov.
The No. 3 ranked heavyweight, Lewis looms as a possible title challenger for reigning champion Francis Ngannou — a match-up UFC President Dana White is keen to see.
The pair fought previously in 2018, Derrick getting the chocolates in one of the most abysmal fights ever to take place in the Octagon.