"Absolutely," Hampton said when asked if she saw the loss of so many seeds as an opportunity for her.
"The top half of the draw has kind of fallen apart but also you have unseeded Venus Williams, which is a bit of a tough one."
Williams survived a tough three-setter against experienced Austrian Yvonne Meusburger but her form has so far been erratic - plenty of winners but also numerous unforced errors - and Hampton will fancy her chances if the pair meet in Friday's semifinals.
Before that, she is due to take on the winner of the match between Konjuh and Lauren Davis, who breezed past New Zealand's Marina Erakovic in her first-round match.
Hampton is the third-ranked American behind Serena Williams (No 1) and Sloane Stephens (12) but further down in the profile stakes with the US public.
"It's OK," she said. "It has its advantages. No one really knows who I am so I can fly under the radar a little bit. I would like some exposure.
"Maybe not [as much as Venus]. It comes with the territory. If I do well, I'm going to get more exposure and I will have to embrace it."
That might come if she continues her upward trajectory. Last year she played in her first WTA final (Eastbourne), appeared in three semifinals and made the third round at both the US Open and Wimbledon and fourth round at Roland Garros.
Those results helped "prove I can compete with the top players and win".
Flipkens also came to Auckland on the back of her best year on tour highlighted by a semifinal appearance at Wimbledon and US$1.1 million ($1.3 million) in prizemoney.