He powered home to beat Australian record-holder and London Olympic medallist Christian Sprenger and leading Chinese breaststroker Shuai Wang.
It was Snyders' third victory of the series and his 10th podium placing from 12 starts on the World Cup circuit.
His fellow Swimming New Zealand high performance centre teammate Melissa Ingram settled for second in the 200m backstroke, following three straight wins over the distance in Stockholm, Moscow and Berlin.
Ingram clocked 2:05.35 to be half a second behind leading Chinese hope Yanxin Zhou, a reversal of their battle at the same meet last year when the Kiwi edged home for the win.
It was Ingram's 10th podium placing in the series.
North Shore's Mitchell Donaldson was the other finalist, finishing seventh in the 400m individual medley in his World Cup debut.
Earlier North Shore's Dylan Dunlop Barrett was 21st fastest in heats of the 400m freestyle and Jessica Marston (West Auckland Aquatics) 22nd fastest in heats of the 800m freestyle.
The meet concludes tomorrow before moving to Tokyo and then Singapore to complete the FINA Arena World Cup circuit.
Day 1 finals:
50m breaststroke: Glenn Snyders (NZL) 26.64, 1; Christian Sprenger (AUS) 26.74, 2; Shuai Wang (CHN) 26.86, 3.
400m individual medley: Zhixian Yang (CHN) 4:05.62, 1; Travis Mahoney (AUS) 4:09.69, 2; Feilian Mao (CHN) 4:10.68, 3. Also: Mitchell Donaldson (NZL) 4:21.94, 7.
400m freestyle: Matthew Stanley (NZL) 3:40.74, 1; Michael Klueh (USA) 3:41.62, 2; Yunqi Li (CHN) 3:41.83, 3.
200m backstroke: Yanxin Zhou (CHN) 2:04.81, 1; Melissa Ingram (NZL) 2:05.35, 2; Anqi Bai (CHN) 2:06.78, 3.