"You have to take that mindset over there," Moore said.
"We want to be really proud of the way we finish the season and this is a key part of that, going over there.
"If you look at our games against the New Zealand teams this year, we've done some good stuff. We just haven't quite played well enough for 80 minutes."
The Highlanders, who will travel to play either the unbeaten Crusaders in Christchurch or the Lions in Johannesburg in the first week of the play-offs, are returning for their first Super Rugby match since the international break.
Before losing to the Crusaders in their last clash before the British and Irish Lions series, they had strung together a franchise-record nine wins in a row.
They will be close to full strength on Friday, with All Blacks pair Ben Smith and Aaron Smith rested, but Liam Squire and Lima Sopoaga will make their return from long-term injuries.
The Reds landed in Queenstown on Wednesday and made the nearly four-hour trek over frozen roads to Dunedin, where the undercover Forsyth Barr Stadium will provide some respite from the bone-chilling cold.
Queensland Reds:
1. Sef Fa'agase, 2. Stephen Moore (C), 3. Taniela Tupou, 4. Rob Simmons, 5. Izack Rodda, 6. Caleb Timu, 7. George Smith, 8. Adam Korczyk, 9. James Tuttle, 10. Quade Cooper, 11. Eto Nabuli, 12. Duncan Paia'aua, 13. Campbell Magnay, 14. Izaia Perese, 15. Karmichael Hunt
Reserves: 16. Alex Mafi, 17. Markus Vanzati, 18. Sam Talakai, 19. Kane Douglas, 20. Reece Hewat, 21. Moses Sorovi, 22. Hamish Stewart, 23. Jayden Ngamanu