Lock Sam Whitelock, named in the starting line-up to play Chris Boyd's team despite falling ill with a virus, was a late withdrawal but should be well enough to travel. Several players in his squad were ill during the week, Blackadder said.
"If anything, it will give us a chance to freshen up and allow us to take a fit team away," he told the Herald. "This is the time of the season when you need to be together as a group, and our time in South Africa will help us do that."
Perhaps unlucky to concede a try on the stroke of halftime at AMI Stadium, which cost them the lead, the Crusaders failed to fire an attacking shot in the second half. The Hurricanes were also disadvantaged when losing Ngani Laumape before kickoff, but the rejigged midfield of Willis Halaholo and Jason Woodward cut the Crusaders to pieces at times.
"I was disappointed with our performance, but I take nothing away from the Hurricanes, they played well and put us under a lot of pressure. We knew they would bring line-speed on defence and we failed to cope with it, so there is a lesson there."
The defeat was the Crusaders' fourth this season - all have come against New Zealand opponents, with the Chiefs (twice), Highlanders and now Hurricanes proving too good.
Blackadder has yet to announce his intentions for next year - recent British reports suggest he and assistant Tabai Matson could be heading to Bath - but his time at the franchise will soon come to an end.
"Everything now is a one-off game," he said.
2016 Super Rugby quarter-final draw
Fri at 8pm: Brumbies [4] v Highlanders [5] at GIO Stadium, Canberra
Sat at 7.35pm: Hurricanes [1] v Sharks [8] at Westpac Stadium, Wellington
Sun at 2.30am: Lions [2] v Crusaders [7] at Ellis Park, Johannesburg
Sun at 5am: Stormers [3] v Chiefs [6] at Newlands, Cape Town
* Regular season finish in brackets