Luke Jacobson could also be in line to start in the loose forwards, with Lachlan Boshier under an injury cloud. Should Boshier be unfit, Jacobson will start and Bay of Plenty forward Jesse Parete will make his debut from the bench.
Young back Levi Aumua was also in line for a debut of the bench.
The Chiefs come into the match on the back of a bye, and meet a Jaguares side who are enjoying a successful road trip.
The Argentinean side have claimed back to back wins in recent weeks, knocking off the Brumbies in Canberra and the Blues in Auckland.
"This will be a really tough game - from a win against the Brumbies to beating the Blues in Auckland is a great feat, so they are showing their worth. We certainly have been analysing them and getting ready for the attack that they are going to bring. They're strong in their set piece and defensively we will be tested."
Chiefs: Charlie Ngatai (cc), Toni Pulu, Anton Lienert-Brown, Alex Nankivell, Solomon Alaimalo, Damian McKenzie, Te Toiroa Tahuriorangi, Liam Messam, Sam Cane (cc), Lachlan Boshier/Luke Jacobson, Tyler Ardron, Michael Allardice, Angus Ta'avao, Liam Polwart, Karl Tu'inukuafe. Reserves: Nathan Harris, Sam Prattley, Jeff Thwaites, Jacobson/Jesse Parete, Pita Gus Sowakula, Brad Weber, Marty McKenzie, Levi Aumua.
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