While Retallick would be available for the match, fellow Chiefs Sam Cane (concussion), Damian McKenzie (All Blacks stand down week) and Sean Wainui (shoulder) were are set to be left out of the final regular season match.
Coach Colin Cooper said with their spot in the playoffs already booked, there was no point in risking Cane, who was cleared to play after picking up a head knock in the side's win over the Brumbies at the weekend.
"Sam's not a hundy," Cooper said. "He passed his tests, but he's still not where he should be."
The Chiefs made an interesting call in leaving McKenzie's last All Blacks stand down week for the final round. With fourth place still a possibility, the Chiefs will try to knock over the Hurricanes without their attacking star.
Cooper said it came down to making sure they had their best team on the field over the past two weeks in what he deemed to be must-win games.
"We needed to beat the Highlanders and we needed to beat the Brumbies, and we couldn't leave Damian out," he said.
"To the critics who think we should have rested Damian earlier, we'd have loved to. We just didn't have the time with losing players, the inexperience of the guys coming in next, we needed to have our most experienced and talented players to help them."
It would be a big surprise to see the Chiefs beat the Hurricanes by enough points to see them secure fourth place, and Cooper said that wasn't how the team were thinking in the lead up to Friday's game. The match shapes up as the last at home in a Chiefs jersey for a number of players, including their most-capped stalwart Liam Messam.
"We still want to just go as hard as we can to try and win the game without a whole lot of if they do this and we do that – I don't like a lot of clutter, I like having a real aim and a goal of what we've trying to do, and that is to farewell these boys if it is their last game in Hamilton."