Replacement hookers Ash Dixon and Motu Matu'u are also both in question, which means a collection of players have been bracketed on the bench.
Reggie Goodes is the first-choice to cover the possibility of both Franks and the hookers being unavailable, with Mike Kainga and Brendon Edmonds named as cover if required.
The Hurricanes are firmly in the playoff picture but need another win this weekend to consolidate their spot in the top six on the Super Rugby ladder.
Hurricanes: Matt Proctor, Cory Jane, Conrad Smith (captain), Alapati Leiua, Julian Savea, Beauden Barrett, TJ Perenara, Victor Vito, Jack Lam, Faifili Levave, James Broadhurst, Jeremy Thrush, Jeffery Toomaga-Allen, Dane Coles, Ben Franks/Reggie Goodes. Reserves: Ash Dixon/Motu Matu'u/Reggie Goodes/Mike Kainga, Chris Eves, Reggie Goodes/Brendon Edmonds, Brad Shields, Ardie Savea, Chris Smylie, Tim Bateman, James Marshall.