Scott Williams: Carried off after suffering a serious knee injury during Wales' Pool A victory over England at Twickenham.
Hallam Amos: Damaged shoulder during the England game as Wales' injury woes continued at an alarming rate.
ITALY
Andrea Masi: The Wasps back damaged his Achilles during the opening pool game against France.
Luca Morisi: Suffered a knee injury and went off early during Italy's warm-up clash against Wales, ending his participation in the competition.
Angelo Esposito:
Damaged his shoulder before the tournament started and was ruled out of World Cup contention.
Jean de Villiers the captain of South Africa lies on the ground injured during the International match between Wales and South Africa. Photo / Getty Images
CANADA
Connor Braid: The versatile back suffered a broken jaw during Canada's Pool D encounter against Italy in Leeds, ruling him out of the tournament.
Jason Marshall: Marshall was an early injury casualty for Canada, with his place being taken by Jake Ilnicki.
Waisea Nayacalevu: Wing Nayacalevu suffered a World Cup knockout blow when he damaged his knee during the Pool A game against Australia.
ENGLAND
Billy Vunipola: The number eight suffered a knee ligament strain in the defeat against Wales and a scan revealed he will be sidelined for six weeks.
FRANCE
Yoann Huget: One of France's most potent attackers suffered a knee injury in the game against Italy, ending his interest in the tournament.
SCOTLAND
Stuart McInally: The Edinburgh hooker featured for the Scots against Italy in Turin last month but a neck injury cost him his place in Vern Cotter's travelling party to England.
Grant Gilchrist: The Scotland lock suffered a groin injury in Sunday's 39-16 win over the United States and will not be back in time to play a further part in the tournament.
Jean de Villiers: The Springboks skipper, who has endured a terrible time with injuries in recent months, suffered a tournament-ending broken jaw in the pool game against Samoa, and then retired from Test rugby.
SAMOA
Logovi'I Mulipola: The Leicester prop was named in Samoa's World Cup squad, but he was then ruled out through injury and ex-Saracens forward Census Johnston replaced him.
UNITED STATES
Scott LaValla: LaValla suffered an injury during pre-tournament training and was replaced by Matt Trouville.
ARGENTINA
Matias Diaz: Diaz sustained a World Cup-ending injury just hours after the Pumas' squad was announced. His misfortune meant a call-up for fellow prop Juan Pablo Orlandi.