With Pocock returning, there is no room for long-time regular Scott Fardy in the match-day 23.
Cheika kept the All Blacks guessing until midday on match eve of the final transtasman showdown of the year before revealing his side.
"We've been trying guys in different combinations at training and trying to find the best ways to maximise the talents of the guys that we have," Australian defence coach Nathan Grey said.
"He's got a lot of experience playing in that position at Super Rugby. He's a big body, carries the ball very well and he's got a good passing game that he uses, and he's got good speed.
"All those attributes are very positive to have in a 12. He defends there at 12 anyway for us so he's used to being in that environment."
Cheika agonised over whether or not to thrust rookie locks Rory Arnold and Adam Coleman into the Eden Park cauldron or recalling the reliable second-row pairing of Kane Douglas and chief lineout caller Rob Simmons.
He eventually kept faith in Coleman and Arnold, while also retaining Lopeti Timani at No 8 after his starring role in Australia's last-start win over Argentina at Twickenham.
The Wallabies are bidding to break a 30-year hoodoo at Eden Park as well as deny the All Blacks a record 18th consecutive win on Saturday night.
Wallabies: Israel Folau, Dane Haylett-Petty, Samu Kerevi, Reece Hodge, Henry Speight, Bernard Foley, Nick Phipps, Lopeti Timani, Michael Hooper, Dean Mumm, Adam Coleman, Rory Arnold, Sekope Kepu, Stephen Moore (c), Scott Sio. Reserves: James Hanson, Tom Robertson, Allan Ala'alatoa, Rob Simmons, David Pocock, Nick Frisby, Quade Cooper, Sefa Naivalu.