Simmons, 28, was dropped twice last year by Cheika, including being sent back to play in the National Rugby Championship after the Wallabies were belted in the Bledisloe opener.
The 72-Test lock is coming off a lacklustre Super Rugby season and was recently released from his contract with the Queensland Reds, with coach Nick Stiles saying he lacked aggression.
Cheika will finalise his bench after Friday's captain's run in Dunedin, with Lopeti Timani and Jack Dempsey battling it out for the same loose forward spot.
Australia must win on Saturday to avoid a 15th consecutive Bledisloe Cup series defeat.
The last time they won in New Zealand was in Dunedin in 2001 at the now-defunct Carisbrook, but they have never won at Forsyth Barr Stadium, the new indoor venue that replaced it.
WALLABIES: 15 Israel Folau, 14 Dane Haylett-Petty, 13 Tevita Kuridrani, 12 Kurtley Beale, 11 Henry Speight, 10 Bernard Foley, 9 Will Genia, 8 Sean McMahon, 7 Michael Hooper (capt), 6 Ned Hanigan, 5 Adam Coleman, 4 Rob Simmons, 3 Allan Alaalatoa, 2 Stephen Moore, 1 Scott Sio. Reserves: 16 Tatafu Polota-Nau, 17 Tom Robertson, 18 Sekope Kepu, 19 Rory Arnold, 20 Lopeti Timani/Jack Dempsey, 21 Nick Phipps, 22 Reece Hodge, 23 Curtis Rona.
- AAP