Sam Underhill moves into the back row with Chandler Cunningham-South dropping to the bench.
“I’m pleased with the progress we are making,” said Borthwick.
“Without doubt, New Zealand are one of the best teams in the world and facing them is always a special challenge.”
England round off their Autumn internationals when they face Argentina at Twickenham on November 23.
England side to face All Blacks
1 Fin Baxter, 2 Jamie George, 3 Joe Heyes, 4 Maro Itoje (capt), 5 Alex Coles, 6 Guy Pepper, 7 Sam Underhill, 8 Ben Earl, 9 Alex Mitchell, 10 George Ford, 11 Immanuel Feyi-Waboso, 12 Fraser Dingwall, 13 Ollie Lawrence, 14 Tom Roebuck, 15 Freddie Steward.
Replacements: 16 Luke Cowan-Dickie, 17 Ellis Genge, 18 Will Stuart, 19 Chandler Cunningham-South, 20 Tom Curry, 21 Henry Pollock, 22 Ben Spencer, 23 Marcus Smith