Also in the forwards, Sam Cane starts at openside flanker with Victor Vito on the blindside; Jeremy Thrush and Patrick Tuipulotu are the locking duo in the second row. In the front row, hooker Nathan Harris gets his first test start after coming off the bench against Argentina last month. Joe Moody also gets his second test start at loosehead prop with Charlie Faumuina at tighthead prop.
Young Counties Manukau and Chiefs halfback Augustine Pulu has the opportunity to make his test debut from the bench, while All Blacks test century-maker and world rugby's leading points scorer, first five-eighth Daniel Carter also making his return from injury from the bench. Wing Julian Savea has also been named as the outside back cover.
In the forwards reserves, the All Blacks have the experienced 120-test veteran Keven Mealamu to call on, together with his fellow front rowers Wyatt Crockett and Ben Franks. Brodie Retallick is the reserve lock, with Liam Messam reserve loose forward.
"This is going to be an exciting occasion for the team, playing the USA in front of a record crowd here in Chicago, and it's great to be here representing the All Blacks and New Zealand," All Blacks coach Steve Hansen said.
"It's another chance for those selected to pull on the jersey and play well."
"While we are giving a number of players another opportunity this weekend, our expectation is that they will play to the highest level and we get a quality performance."
The All Blacks and USA have played each other three times, most recently at the 1991 Rugby World Cup in Gloucester when the All Blacks won 46-6.
Starting XV (tests in brackets)
1. Joe Moody (5)
2. Nathan Harris (1)
3. Charlie Faumuina (22)
4. Jeremy Thrush (4)
5. Patrick Tuipulotu (5)
6. Victor Vito (24)
7. Sam Cane (21)
8. Kieran Read (captain) (69)
9. TJ Perenara (7)
10. Aaron Cruden (35)
11. Charles Piutau (11)
12. Sonny Bill Williams (19)
13. Ryan Crotty (9)
14. Cory Jane (52)
15. Israel Dagg (43)
Reserves:
16. Keven Mealamu (120)
17. Wyatt Crockett (33)
18. Ben Franks (37)
19. Brodie Retallick (33)
20. Liam Messam (35)
21. Augustine Pulu *
22. Daniel Carter (100)
23. Julian Savea (28)