The first photo allegedly shows Lane, who played for the Warriors in 2016, holding a plastic bag containing the substance with another showing him putting something in his mouth.
There is no suggestion, however, of what the substance might be or that any illegal substance was consumed.
"Pictures have emerged in the last 24 hours of Lane at Mad Monday last year with the Manly Sea Eagles, with a plastic bag, which contains white substance," Daily Telegraph reporter Phil Rothfield told NRL 360.
"We're not saying he took the drug, but we're reporting the fact the NRL integrity unit has the photos now, the Eels have the photos and have had preliminary talks with Lane.
"Even though it did happen some time ago, the NRL are concerned about it."
Rothfield went on to describe both the photos and how they were distributed as disturbing.
The Eels issued a statement confirming they were aware of the images but that they "will be making no further comment until the investigation has been completed".
Lane made his debut for the Warriors in round nine of the 2016 season before signing a two-year contract with Manly in 2017.
Lane will meet with the Eels today.
