Newcastle slipped away in the final 10 minutes, courtesy of a series of simple Knights' ball-handling errors.
In contrast, Penrith are second only to the Dragons in making mistakes this season and it showed. Their football, especially near the line, was largely fancy-free. They drew, passed or threaded kicks through the opposition defensive line with ease.
The Panthers also have the lowest average linebreaks per match of any team but that is countered by the most tries scored from kicks.
Second-rower Gavin Cooper's try last night came courtesy of halfback Luke Walsh's precise boot. Lock Luke Lewis also slipped a grubber through for centre Michael Jennings.
The first quarter proved crucial. The Knights could not compete against the Panthers' ability to complete seven out of eight (88 per cent) sets. Newcastle also missed nine tackles during that period compared to a perfect record by the Panthers.
The Knights struggled to get field position to dilute the Penrith dominance. When they did, they were too often impotent near the line. The Panthers had few problems with their solid defence.
Penrith move to second on the table with 18 points, a position dependent on how Manly fare against Brisbane later today.
Newcastle remain 12th on 10 points but could slip a further spot if North Queensland beat South Sydney by four points or more tomorrow.
Penrith 28 (G. Cooper, B. Tighe 2, M. Jennings, L. Coote tries, M. Gordon 4 goals) Newcastle 10 (A. Uate, J. McManus tries, K. Gidley goal). Halftime: Penrith 18-0.