The incident was eerily similar to the one which cost Pritchard a suspension last year when he hit Cronulla pivot Wade Graham, and he faces a nervous wait for the match review committee's findings.
New Canterbury coach Des Hasler's frustrations were tempered somewhat when a sweet Pritchard short ball put Josh Morris in with what proved to be the match-winner four minutes later before Bryson Goodwin crossed in the dying minutes.
It was hardly the type of performance that would have excited Hasler, however, the Bulldogs struggling with discipline and handling issues.
Penrith went up 12-0 via tries to Travis Burns and Michael Jennings - the second a positive sign for Panthers' fans after Jennings had to wait until round 13 to score his one and only four-pointer in 2011.
The Bulldogs couldn't get anything going, and it was against the run of play that they halved the deficit when Josh Reynolds crossed in the 32nd minute.
It became even worse for the home side when last year's leading tryscorer Ben Barba opened his 2012 account, backing up a long-range Corey Payne bust six minutes after the restart.
Barba almost went from hero to villain moments later when he spilled a bomb near his own line, only for Lachlan Coote to spill the bouncing ball with the line wide open.
Penrith edged ahead when Luke Walsh added a penalty goal just before the hour, but it wasn't enough in the end.
CANTERBURY 22 (B Barba B Goodwin J Morris J Reynolds tries S Turner 3 goals) bt PENRITH 14 (T Burns M Jennings tries M Gordon 2 L Walsh goals) at Centrebet Stadium. Referee: Jason Robinson, Phil Haines. Crowd: 9,385.