And Brisbane - already without ex-Test backrower Sam Thaiday - were soon reeling from the pre-game withdrawal of Queensland hopeful Ben Hannant (groin), replaced by David Stagg.
Still, the Titans grabbed an 8-4 halftime lead ahead of 31,380 before Brisbane looked to have snuck ahead in the 43rd minute.
Backrower Alex Glenn crossed, only for the video referees to give the red light after dubiously ruling that Brisbane forward Jarrod Wallace had obstructed the defence.
But the Broncos were not to be denied 14 minutes later when winger Dale Copley sealed a double, running off veteran centre Justin Hodges to lock up the scores 8-8.
And Brisbane jumped to a 14-8 buffer when Test utility Matt Gillett crashed over in the 64th.
Gold Coast were denied a miraculous Anthony Don four-pointer off a kick in the 67th when the video referee picked up a David Taylor knock-on in the lead-up.
Corey Parker's 70th minute penalty drilled another nail in the Titans' coffin before centre Jack Reed's 74th try sealed the result.
Gold Coast drew first blood when Sezer potted a ninth minute penalty.
But Brisbane appeared to have the upper hand in a dour struggle when winger Copley fed off a sublime Hodges face ball to cross in the 31st.
Yet the visitors held the upper hand at the main break 8-4, Don crashing over in the 35th minute.
-AAP