Penrith centre Michael Jennings becomes the first player in almost 30 years to be chosen from reserve grade to represent NSW.
Parramatta's No.1 Jarryd Hayne is expected to play on the wing.
Stuart will hand debuts to Cronulla's Todd Carney, North Queensland's James Tamou and Manly utility Jamie Buhrer, who's the surprise call-up.
Manly's giant Test backrower Tony Williams is also included for the first time despite having spent the past six weeks on the sidelines as he serves a seven-game ban for a lifting tackle.
NSW squad (in alphabetical order): Greg Bird, Jamie Buhrer, Todd Carney, Ben Creagh, Robbie Farah, Paul Gallen (capt), Jarryd Hayne, Michael Jennings, Luke Lewis, Trent Merrin, Josh Morris, Mitchell Pearce, Brett Stewart, Glenn Stewart, James Tamou, Tony Williams, Akila Uate.
-AAP