Centre Tom Taylor kicked 23 points but it was not enough as Pau lost 28-30 at home to Luke Braid's Bordeaux-Begles. Colin Slade wore the No 10 jersey for Pau while lock Daniel Ramsay came off the bench, only to be yellow carded.
Carl Axtens, Joe Tekori and Census Johnston featured for Toulouse in their decisive 31-3 win over Tino Nemani's Grenoble.
Benson Stanley, Fritz Lee and Isaia Toeava all played for Clermont in the 29-19 victory over Castres.
There was plenty of drama in England's Aviva Premiership.
Tries to Johnny Leota and Halani Aulika helped Sale Sharks to a 34-30 win over Leicester Tigers. Jimmy Gopperth continued on his merry way, kicking six goals as Wasps crushed Winston Stanley's Harlequins 47-18.
The quartet of Tusi Pisi, Mark Sorenson, Anthony Perenise, and Jack Lam were powerless to stop Saracens crushing their Bristol side 39-0.
Northampton's Ken Pisi, George Pisi and Michael Paterson all started as the Saints edged Thomas Waldrom's Exeter Chiefs 20-19.
Kahn Fotuali'i's Bath beat John Afoa's Gloucester 15-6, while Jackson Willison's Worcester defeated Newcastle 11-9, despite two goals by the Falcons' Mike Delany.
In the Guinness PRO12, Gareth Anscombe scored all 13 points for Cardiff Blues in their 16-13 defeat to Jamison Gibson-Park's Leinster. Hadleigh Parkes' Scarlets beat Treviso 22-6, the latter fielding Jayden Hayward (15), Filo Paulo (4) and Dean Budd (7).
Charlie Piutau's Ulster had a narrow 9-7 win over Ma'afu Fia's Ospreys.
First five Tyler Bleyendaal kicked four conversions in Munster's 49-5 shellacking of Zebre, while hooker Corey Flynn scored an important try in Glasgow's 26-17 victory over Nick Crosswell's Dragons.
Defending champs Connacht finally recorded their first win of 2016-17, a 28-15 affair over John Hardie's Edinburgh. Bundee Aki, Jake Heenan and Tom McCartney all played for Connacht.