With the Knights missing halfback Mitchell Pearce and prop Daniel Saifiti (State of Origin) and fullback Kalyn Ponga (injury), the Warriors will look to take advantage of a weakened Newcastle side to try and keep even a glimmer of hope in their season.
"We've got to get these points," Tuivasa-Sheck said. "We've got to get a run going."
The Warriors go into a period on their schedule where they will be away from Mt Smart Stadium for the best part of a month, with their next four games being away to Newcastle and the Brisbane Broncos, in Wellington against the Cronulla Sharks, and away to the Parramatta Eels.
It's not necessarily the worst thing for the Warriors, who have not won at Mt Smart Stadium in their past five matches at the venue, winning just two of seven this season at what used to be their fortress.
On the whole, they've performed better this season when on the road, with three wins and some agonisingly close defeats to some of the league's top teams.
"On the road, we need to start making it happen," Tuivasa-Sheck said.