Former Auckland schoolboy sensation Taniela Tupou has been ruled out of tonight's Bledisloe Cup test - which would have been his first clash against the All Blacks.

The Reds prop and former Sacred Heart College student has suffered a hamstring injury and has been replaced on the bench by Jermaine Ainsley, according to the Daily Telegraph.

Ainsley, a prop for the Melbourne Rebels, is New Zealand born and raised and attended Otago Boys' High School. He is set to make his Wallabies debut.

It's a second front row injury for the Wallabies on the eve of the Bledisloe Cup and Rugby Championship opener after Scott Sio was ruled out with a shoulder injury.

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Wallabies: 15. Israel Folau 14. Dane Haylett-Petty 13. Reece Hodge 12. Kurtley Beale 11. Marika Koroibete 10. Bernard Foley 9. Will Genia 8. David Pocock 7. Michael Hooper (captain) 6. Lukhan Tui 5. Adam Coleman 4. Izack Rodda 3. Sekope Kepu 2. Tatafu Polota-Nau 1. Tom Robertson.

Reserves: 16. Tolu Latu 17. Allan Alaalatoa 18. Jermaine Ainsley 19. Rob Simmons 20. Pete Samu 21. Nick Phipps 22. Matt Toomua 23. Jack Maddocks.