"Ryan is a natural choice (as captain). He's one of our leaders and is well versed in the demands of the role."
The loss of Tuivasa-Sheck is a blow to the Warriors who, despite having the Kiwis test spine on their books, have been unable to get all of their big names on the field together for extended periods.
Tuivasa-Sheck, along with hooker Issac Luke, arrived as marquee signings last year, but the former Sydney Roosters premiership winner made only seven appearances before suffering a season-ending ACL injury in April.
The addition of five-eighth Kieran Foran for this season is yet to pay dividends, with the NRL suspending him for the first two rounds and a slower-than-expected recovery from shoulder surgery further delaying his highly anticipated debut.
The scenario is made more unpalatable following Tuivasa-Sheck's commanding early season form, which provided a glimpse of the side's undoubted attacking potential together with a fully fit Luke and halfback Shaun Johnson.
After building his confidence in the preseason trials, Tuivasa-Sheck turned in a terrific performance in the round one win over Newcastle, topping the running metres with 251 from 21 carries while making several threatening runs to get his side on the front foot.
The Warriors attack suffered noticeably following his departure in the 27th minute against the Storm and the home side failed to add to their score throughout the remainder of the match.
Lolohea was expected to turn out for the Warriors' reserve grade side in Saturday's clash against Wests Tigers in Sydney and will likely come in for close inspection from the Bulldogs following two patchy defensive displays against Newcastle and Melbourne.
Back-up No7 Mason Lino has also been omitted from the initial 21-man squad and will travel across the Tasman to play at Campbelltown Stadium on Saturday.