As expected, Pulse coach Yvette McCausland-Durie opted for fresh legs and new combinations on court in a bid to rest her stellar starting seven.
After spending most of the season on the bench, Silver Ferns shooter Ameliaranne Ekenasio made just her second start for the Wellington side alongside the accurate Aliyah Dunn.
Ekenasio found good connection with Dunn in and around the shooting circle while her experienced presence made for a settled Pulse attacking unit.
Star shooter Maria Folau was back in the shooting circle for the Mystics with her Silver Ferns counterpart Bailey Mes. Folau's presence made for a hefty task for Pulse captain Katrina Grant and fellow defender Sulu Fitzpatrick as the internationally renowned shooter kept the scoreline close for most of the opening quarter.
As Grant and Fitzpatrick's combination took full effect in the second period of the clash, Mes became increasingly hesitant under the hoop, sinking just three of five goals. But with Pulse midcourter Karin Burger making an abrupt exit from the court with a sprained ankle, the Mystics looked eager to capitalise on the absence of the home side's key player.
Harrison led her side from the front with plenty of 'Harrison Hoists' and innovative defensive tactics that kept the Pulse guessing, but the resilient skipper's outstanding form wasn't enough alone to see the Mystics catch up with the front-running home side.
The Mystics' low shooting percentage continued to let down their chances of a comeback in the final quarters. With midcourter Elisapeta Toeava struggling to find space from the circle edge as the Pulse defence tightened, it forced Folau to carry her side with plenty of long-range shots.
Although desperate to make back lost ground in their final shot at making the playoffs, the Pulse took full control in all areas across the court, closing out the clash to deliver their home crowd another exciting win.
The Mystics finish their season in fourth place on the Premiership ladder with 17 points from seven wins and eight losses.